How Effective Is Nicosan For The Treatment Of Sickle Cell ?

Here are a couple of interesting/promising articles about a new sickle cell drug developed in Nigeria called nicosan (aka niprisan) :-

Nigerian President Olusegun Obasanjo Launches Xechem's Sickle Cell Drug, NICOSAN(TM), in Nigeria


Demand for New Sickle Cell Drug NICOSAN(TM) Far Exceeds Supply


If these articles are anything to go by then this is a huge breakthough for Nigerian scientists and more importantly for sickle cell sufferers worldwide.

Is this for real or mere hype?

I am curios to know how effective this drug is?

Does anyone have any relevant information from personal experience or hear-say?. I would also be particularly interested in hearing from anyone who may have participated in the clinical trials leading to the NAFDAC approval.



25 answers

Reproduce should have a synonym.


@smart choice: still waiting



[quote author=oluplus][/quote]

pls put a fone no...


[quote author=smartchoice]

PM me[/quote.


can you reproduce it or not?


Then i need to understand your question sir.


I'll need a lot money, a well stocked laboratory and bulk manufacturing plant.


Ade can you reproduce the drug?


Please and please, where can I get these drugs, nicosan, solamin. Please save a soul. Urgent response will be appreciated.



The pharmaceutical industry has more to gain when people are sick than when they are well.

Therefore, they manufacture drugs that only relieve symptoms but do not cure disease. There’s a vested interest in keeping people sick because the big bucks are in drugs for ongoing diseases. And yet, the pharmaceutical companies’ clever propaganda to make themselves look like the savior of all mankind - a savior that finds “cures” for diseases and saves people’s lives - has successfully deceived us into regarding them with a sense of awe, reverence and respect for all that they do for human health.

The irony of it all is that more people have died from preventable diseases than all the wars of the world combined as a direct result of the pharmaceutical business. These deaths were not just from the use of drugs (as in the case of the 106,000 deaths per year from the negative effects of drugs) but from the industry’s suppression of information about non-drug health alternatives that could have kept people from dying.

Pharmaceutical companies routinely use their power and unlimited financial resources to keep doctors from prescribing natural therapies - and their powerful lobbyists even get Congress to disallow established health claims for natural remedies. If you do some research on your own, you’ll find this to be true. They have built an elaborate maze of manipulation, control, infiltration and economic incentives to systematically deceive millions of people into thinking that drugs are the only solution to disease

The deception has become so pervasive that we have been brainwashed into thinking that whenever we are sick or are not feeling well, all we have to do is take a pill to feel better

According to a June 2008 article written by Dr. Joseph Mercola in his popular natural health newsletter,

“As much as the drug companies want you to believe that it’s normal to take medicine every day, it’s not. It is the rare exception that you should ever need to take a drug.”

It is of no comfort that the Food & Drug Administration (FDA), the government agency created to protect public health, makes it a priority to promote drugs and the financial interests of pharmaceutical companies. This is so because many of the FDA’s senior management and members of its advisory committees accept more than $50,000 apiece in corporate grants, contracts and consulting fees from pharmaceutical companies.

It wasn’t until the Vioxx scandal took place that the true nature of the FDA was revealed, along with its leniency toward the industry it’s supposed to be regulating.

In 2004, Merck marketed Vioxx for the treatment of arthritis and other conditions causing chronic or acute pain. Later, it was discovered that Merck had deliberately suppressed the heart attack risks of Vioxx. The international medical community has criticized the FDA for not only being “asleep at the wheel” while this was happening, but also of acting in collusion with Merck to cover up the truth.

The irresponsible behavior of the FDA caused Dr. Richard Horton, editor of The Lancet (one of the most respected medical journals in the world) to state,

“This discovery points to astonishing failures in Merck’s internal systems of post-marketing surveillance, as well as to lethal weaknesses in the U.S. Food and Drug Administration's regulatory oversight.”

Vioxx has since been taken off the market.

Instead of relying on drugs and paying close to a trillion dollars to the pharmaceutical cartel for drugs that do not cure (and often cause harm, or even death), we must rely more on natural approaches for achieving optimal health.

The answer is this: Disease is big business.

Americans are spending over $2 trillion dollars on health care, and that figure is expected to reach the $3 trillion mark by the end of the decade. Over $1 trillion dollars of the spending is on pharmaceutical drugs.

With these kinds of revenues, there is no incentive on the part of the pharmaceutical industries to promote better health. They are the most profitable industry in the world, enjoying average profit margins of 30,000% to 50,000% on pharmaceutical drugs over the cost of raw materials. Sometimes, their markups can be as high as 569,000%!

The average business person in his right mind wouldn’t dare walk away from such profits, and would do almost anything to ensure that the trillion-dollar cash cow remains intact.

As a result, the pharmaceutical industry has assembled a pharma-cartel consisting of an army of lobbyists that influence not only the entire medical industry but also the U.S. Congress; and by extension, the lives of the entire American population.

Pharmaceutical companies spend enormous amounts of money to get doctors to prescribe their drugs to patients; to get the American public to believe, via the barrage of drug commercials, that they’ve got a health problem; and to get Congress to pass legislation that ensures their continued profitability.



- Sickle



- Clinical



a non-toxic,


pharmaceutical, product for the treatment of

Sickle Cell Disease (SCD). NicosanTM is

obtained from the mixture of four Nigerian

plant materials e.g. Piper guineese (Seeds),

Pterocarpus Osun (Stems), Eugenia

caryophyllum (Fruits), Sorghum bicolor

(Leaves), in a standard ratio which produce

a hygroscopic, reddish-brown powder with

a pungent odour.

In July, 2002, Xechem acquired exclusive

worldwide license from the Ministry of

Health, Federal Government of Nigeria to

develop and market NICOSAN™ (HEMOXIN™

in the US).

NICOSAN™ (HEMOXIN™) was shown to be a

safe and efficacious medicine for the

management of patients with Sickle Cell

Disease. As published in the May 2003

issue of the British Journal of Hematology,

Dr.Toshio Asakura and colleagues from

Children's Hospital of Philadelphia (CHOP),

USA and the University of Pennsylvania

demonstrated the anti-sickling effects of

NICOSAN™ (HEMOXIN™) in transgenic mice.

The quality and standardization of the

medicine has been tested and proved by

High Performance Liquid Chromatography

(HPLC) and bioassay.

NICOSAN™ Characteristics

A 100 % Nigerian indigenous Product.

Product available in Capsules, pleasant

tasting with no known side effects.

Dose determined and Clinical Trials


The pricing strategy will favor the poor and



1. It is used for prophylactic management

of sickle cell disease (SCD).

2. It has potent anti sickling effect on

sickled erythrocytes, obtained from patients

with SCD and on transgenic mice that

produced human sickle hemoglobin, thus

useful in preventing painful crisis

experienced by SCD patients.

3. It reduces hypoxic stress experienced by

SCD patients (due to trapping of sickle cell

in lungs), drastically.

4. It removes the incidence of blood

transfusion in SCD PATIENTS.

5. It prevents clinical sequel (i.e. painful


6. It prevents ocular damage



comes in two

different strengths:

250mg (Children Dose)

350mg (Adults Dose)

It is presented as 30 capsules, packaged in

60ml, HDPE bottles


Adult Dose:

One (1) capsule (350mg) daily at meal time

with water.

Child Dose:

One (1) capsule (250mg) daily at meal time

with water.



Mild non- itching muscular rash

Mild headache.


- Non Toxic

- Higher doses of 2000mg 5000mg/kg

LD50 (A lethal Dose at which 50% of the

population of experimental mice were

expected to die), there was no death


- No kidney or liver damage was observed

both in human volunteers and in

experimental animals during and after the

clinical trials, the drug is safe in humans at


recommended dose.


There is no known contra-indication in

both mice and human to all the active

ingredients. The potash used for extraction

and the binding agent (Lactose) are safe for

human consumption.

No health hazard was observed, when

administered in the proper dosage form.


It can be safely combined, with other

drugs, even the cytotoxic drugs like

Indinavir, Zidovudine, Lamivudine and

Vevirapine used in the management of HIV/


Paracetamol was found to increase the

invivo concentration of NicosanTM care

must be taken, when they are co



There is no known teratogenic effect

produced by NicosanTM, even some

pregnant women who opted (against

clinician's advice) to continue taking

NicosanTM had normal babies.


To be stored in a dry clean place storage

temperature is 25oc. Protect from moisture

and humidity.


NICOSANTM is an effective and safe drug of

choice for the management of sickle cell

disease (SCD).


Keep out of reach of the children don't

exceed the stated dose.


I have the best solution for you... purely herbal and it cures it not managing it, you can check my profile, i ve used Solamin, Nicosan, Carao, Discovite & cell od, all only manages it until i met the real herbal cure. The dosage is 2-8months in both mild & severe cases. The sure thing is within a month of taking the remedy you won't believe the efficacy! If you can come in person to have it or order it there is room for seeing is believing! Therapy herbal- There are several ways to therapy cure of variety of diseases and illnesses through the use of herbs, leaves and roots that are naturally given by mother nature. In Africa , there are good people who have gone far in their research for greater height and using it to cure many diseases and which chemical- based medicines failed to cure such as Sickle Cell, HIV, Cancer and many that will be mentioned as I proceed . Now there are testimonies obtained by many patients who had benefited from our remedies. ILLNESS / DISEASE DURATION OF TIME TO BE CURED Malaria- 2 Weeks Injury / intestinal bleeding- one week Ulcer- 3 weeks Hot track- 2 Weeks Cholera- 1 day Bilharzia ( urination with blood) 3Days Heavy Heart ( breathing ) 1 month Prostate- 6 weeks Low sperm count- 3 weeks Fluid back (female ) 3 Weeks Sickle Cell- 8 weeks Easy Childbirth6 1 Day Dizziness ( eyes turning) 1 week Abnormal heart beat- 1 week Anemia- 3 days Hernia- 1 month Hemorrhoids- 2 Weeks Asthma- 2 Weeks Hiccups- 1 day Stuttering / stammering- 1 month Alcohol Abuse- 1 week Anti Drugs - 1 week Jaundice- 3 days TB- 2 Weeks Ring worm- 2 Weeks Whit low -1 week Internal bleeding- 1 day Cirrhosis- 1month Fibroid- 1 month Cyst ( For women ) 1 month Diabetes- 1 month Rheumatism- 1 month CONTACT ME IF ANY OF THESE ILLNESS IS YOUR PROBLEM!!! +22966088270, sajolive6@gmail.com skype-sajolive


How can i buy nicosan for my child.. pls help


Good to know NICOSAN is out there after months of problems. The drug was developed solely by NIPRD(National institute for pharmaceutical research and development). Since early last year or so, issues with bulk manufacturing, licensing and distribution av surfaced. I can assure you those issues will be put aside soon.


Who's heard of Solamin?


Nicosan is a Nigerian manufactured drug at Sheda, Gwagwalada in Abuja. It ought to be readily available for nigerians, but for some reasons, production is hampered. We hope that very soon production will start in earnest. For full effectiveness patient must take the required dosage regularly.


i read about it a while ago. its nice to know sicklers can live healthy productive with this kind of drug.

but is is readily available? i can't imagine what will happen if they don't take their dosage regularly.


If u are in Abuja, Nicosan is available in some pharmacies in Gwagwalada, Mararaba and in the town, but is quite expensive, ranges from N6,000 to N7,500 depending on whether it is for child or adult.



Is Nicosan presently available in any reputable pharmacy in nigeria

How much is a pack

Direct testimony from Nicosan user

Feedback highly appreciated


@blackhope, its not mere hype, nicosan is actually effective. I've once been with Xechem, the company producing nicosan, b4 d launching, during the period of NAFDAC approval. From real life testimonies pple have commended d effectiveness of d herbal drug, at least it reduces crisis 2 d barest minimum.

But my concern now is d availablity after d closedown of d factory, i do hope dat something will be done fast 2 make d drug available again, cos it is truly a life saver 4 scd patients.


Here are some answers to my earlier question :-


"My son has sickle cell. It is a terrible thing to experience or witness. Whenever he is in crisis, I feel so sorry for him and cry with him. The pains are very severe. In Nigeria, a drug was discovered which I have been using since I got to know about it. For me, it is very effective indeed! But one has to take it every day. It is very expensive considering the low standard of living in Nigeria. The government should assist sickle cell sufferers just as they assist HIV/AIDS patients. Godwin

Godwin Ondoma, Abuja, Nigeria"

If anyone cares to share their experiences that would be great for the benefit of all who suffer from this difficult disease.

Read the full transcript here


Black Hope

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